Clinical and pathological observations and treatment of congenital goitre in kids

Ozmen O., Sahinduran S., Sezer K.

BULLETIN OF THE VETERINARY INSTITUTE IN PULAWY, cilt.49, sa.2, ss.237-241, 2005 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 2
  • Basım Tarihi: 2005
  • Dergi Adı: BULLETIN OF THE VETERINARY INSTITUTE IN PULAWY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.237-241
  • Anahtar Kelimeler: kid, congenital goitre, pathology, thyroid hormones, treatment, HYPERPLASTIC GOITER
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Clinical, pathological and biochemical findings were described in stillborn and live kids affected with congenital goitre. The observations involved 5 stillborn kids with goitre, 5 stillborn kids without goitre, used as control, and 7 live kits with goitre. Grossly, the thyroid glands were visible and palpable in both dead and live kids. Histopathologically hyperplastic goitre was observed in 3 kids and colloid goitre was diagnosed in 2 kids. Plasma T-3, T-4, FT3 and FT4 levels were determined in survived kids. T-3 and FT3 levels were very high and T-4 and FT4 levels were found to be very low. Alive kids treated with Levothyroxine sodium showed a marked reduction in the size of the thyroid glands after two month treatment and their hormone levels were close to the normal ones. Twins or triples were observed to be predisposed to congenital goitre. All the stillborn kids were twins or triplets and were usually found dead. On the other hand, single born kids survived and showed normal growth rate.