Alleviation of prilocaine-induced epileptiform activity and cardiotoxicity by thymoquinone

Akgul, BARIŞ; AYCAN, İLKER; Hidisoglu, ENİS; Afsar, EBRU; Yildirim, Sendegul; TANRIÖVER, GAMZE; COŞKUNFIRAT, NESİL; Sanli, Suat; AYDIN ASLAN, MUTAY

doi:10.1007/s40199-020-00385-2

Alleviation of prilocaine-induced epileptiform activity and cardiotoxicity by thymoquinone

Akgul B., AYCAN İ. Ö., Hidisoglu E., Afsar E., Yildirim S., TANRIÖVER G., ...Daha Fazla

DARU-JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.29, sa.1, ss.85-99, 2021 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 29 Sayı: 1
Basım Tarihi: 2021
Doi Numarası: 10.1007/s40199-020-00385-2
Dergi Adı: DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, CINAHL, EMBASE, International Pharmaceutical Abstracts, MEDLINE, Veterinary Science Database
Sayfa Sayıları: ss.85-99
Anahtar Kelimeler: Prilocaine, Central nervous system, Cardiovascular, Toxicity, Thymoquinone
Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose This study investigated whether thymoquinone (TQ) could alleviate central nervous system (CNS) and cardiovascular toxicity of prilocaine, a commonly used local anesthetic.