Case reports in medicine, cilt.2012, ss.870783, 2012 (SCI-Expanded)
Small cell carcinomas (SCCs) are more often described in
lungs, but rarely laryngeal, pancreatic, stomach, prostatic,
uterine, sweet glands, and esophageal locations are reported
[1, 2]. Esophageal and extrapulmonary small cell Carcinoma
(EPSCC) was described first by McKeown in 1952 [3].
Primary small cell carcinoma of the esophagus (PSCCE)
is a rare, rapidly progressive, and highly metastatic disease
with poor prognosis. The incidence of PSCCE between all
esophageal malignancies is from 0.05 to 2.4% in western
populations, and this rate rises up to 7.6% in Chinese and
Japanese literature [1, 4, 5]. As seen in our case, the cases
with tracheal invasion due to rapid progression of PSCCE,
without the presence of dysphagia in the foreground, admit
to the hospital with the complaint of cough. From this aspect,
we presented a case of extrapulmonary intrathoracic SCC,
because it was both a rare etiology of severe dry cough and
an indicator of rapid progression of PSCCE.