Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn's Disease

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ÜNAL B., BAŞSORGUN C. İ., Gonulcu S. C., Ucar A., Celik F., ELPEK G. Ö.

CASE REPORTS IN MEDICINE, vol.2015, 2015 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 2015
  • Publication Date: 2015
  • Doi Number: 10.1155/2015/348204
  • Journal Name: CASE REPORTS IN MEDICINE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Akdeniz University Affiliated: Yes

Abstract

Here we present an eleven-year-old male patient who had been diagnosed with common variable immunodeficiency (CVID) three years ago due to recurrent sinopulmonary infections. Two years later he had been diagnosed with Crohn's disease (CD) due to diarrhea episodes which were unresponsive to the treatment. Depending on the active gastrointestinal bleeding and perforation he underwent total colectomy. Despite immunoglobulin and antiviral therapies, general condition of patient deteriorated and he died in the postoperative seventh day. Laboratory analysis was seronegative. CMV inclusion containing cells were detected in postmortem biopsies taken from liver, lungs, and lymph nodes.