Spindle cell haemangioma, an unusual presentation


Başsorgun C. İ., Yavuz A., Çelik M. Y., Bayramoğlu Z., Ünal B., Türkoğlu Şen E. B., ...Daha Fazla

34 th European Congress of Pathology, Basel, İsviçre, 3 - 07 Eylül 2022, cilt.481, ss.320

  • Yayın Türü: Bildiri / Özet Bildiri
  • Cilt numarası: 481
  • Doi Numarası: 10.1007/s00428-022-03405-5
  • Basıldığı Şehir: Basel
  • Basıldığı Ülke: İsviçre
  • Sayfa Sayıları: ss.320
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background & objectives: Spindle cell haemangioma (SCH) is a benign vascular tumour that occurs in the dermis or subcutaneous tissue of the hands and feet of young adults. SHC is occasionally associated with Maffucci syndrome, Ollier disease, and Klippel–Trenaunay syndrome.

Methods: An 18-year-old male patient presented with a mass near the lacrimal gland in the left orbital region. Magnetic resonance imaging revealed a 7x13 mm nonspecific mass lesion in the left lacrimal gland localization with contrast enhancement. An excisional biopsy was performed from the masses in the left orbital region and sent to pathology.

Results: Gross examination of the surgical specimen showed the 1.5x1.4x1 cm haemorrhagic lesion. Microscopic examination revealed two different components, thin-walled, large cavernous spaces and spindle epithelioid endothelial cells. There were 1-2 mitotic figures per 10 high-power field. Cellular atypia, atypical mitosis, necrosis, and pleomorphism were not observed. Immunohistochemical examination revealed a positive reaction with CD31 and CD34 in cells lining the vascular spaces.

Conclusion: The case was diagnosed as SCH. SCH is very unusual tumour in the orbital region. SCH should be considered as one of the differential diagnosis in vascular tumours of the orbit. Therefore, immunohistochemical examination should be performed to differentiate it from tumours such as orbital cavernous venous malformations, Kaposi's sarcoma, angiosarcoma and epithelioid haemangioma.