The effect of diabetes mellitus on active avoidance learning in rats: The role of nitric oxide

Kucukatay V., Hacioglu G., Ozkaya G., Agar A., Yargicoglu P.

MEDICAL SCIENCE MONITOR, vol.15, no.3, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 3
  • Publication Date: 2009
  • Journal Name: MEDICAL SCIENCE MONITOR
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: diabetes, lipid peroxidation, learning, nitric oxide, rats, LONG-TERM POTENTIATION, HIPPOCAMPAL SYNAPTIC PLASTICITY, SUPEROXIDE-DISMUTASE ACTIVITY, FLUOROMETRIC-DETERMINATION, SYNTHASE EXPRESSION, LIPID-PEROXIDATION, OXIDATIVE STRESS, HIGH GLUCOSE, STREPTOZOTOCIN, MEMORY
  • Akdeniz University Affiliated: Yes

Abstract

Background: Growing data report memory and other cognitive problems among individuals with diabetes mellitus. Nitric Oxide may play a key role in many physiological and pathological situations. The aim was to investigate the role of NO in diabetes-induced changes hi learning and lipid peroxidation.