Relationship between periodontal findings and the TNF-alpha Gene 1031T/C polymorphism in Turkish patients with Behcet's disease

AKMAN, AYŞE; Sallakci, N.; Kacaroglu, H.; TOSUN, ÖMÜR; Yavuzer, U.; ALPSOY, ERKAN; Yegin, OLCAY

doi:10.1111/j.1468-3083.2008.02678.x

Relationship between periodontal findings and the TNF-alpha Gene 1031T/C polymorphism in Turkish patients with Behcet's disease

AKMAN A., Sallakci N., Kacaroglu H., TOSUN Ö., Yavuzer U., ALPSOY E., ...Daha Fazla

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, cilt.22, sa.8, ss.950-957, 2008 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 22 Sayı: 8
Basım Tarihi: 2008
Doi Numarası: 10.1111/j.1468-3083.2008.02678.x
Dergi Adı: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.950-957
Anahtar Kelimeler: Behcet's disease, clinical findings, disease severity, periodontal status, TNF-alpha-1031T/C polymorphism, NECROSIS-FACTOR-ALPHA, SYSTEMIC INFLAMMATION, ASSOCIATION, HEALTH, SEVERITY
Akdeniz Üniversitesi Adresli: Evet

Özet

Background Genetic factors that predispose individuals to Behcet's disease (BD) and periodontal disease. Tumour necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of both BD and periodontal disease. The relationship with periodontitis and the pathogenesis of BD has not yet been determined.