Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials
CRITICAL CARE, vol.14, no.4, 2010 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 14 Issue: 4
- Publication Date: 2010
- Doi Number: 10.1186/cc9206
- Journal Name: CRITICAL CARE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Open Archive Collection: AVESIS Open Access Collection
- Akdeniz University Affiliated: Yes
Abstract
Introduction: Dead-space fraction (Vd/Vt) has been shown to be a powerful predictor of mortality in acute lung injury (ALI) patients. The measurement of Vd/Vt is based on the analysis of expired CO2 which is not a part of standard practice thus limiting widespread clinical application of this method. The objective of this study was to determine prognostic value of Vd/Vt estimated from routinely collected pulmonary variables.