Systemic toxicity of tacrolimus given by various routes and the response to dose reduction

Akar, Y; Yucel, G; Durukan, AH; Yucel, M; Arici, AYŞE

doi:10.1111/j.1442-9071.2005.00942.x

Systemic toxicity of tacrolimus given by various routes and the response to dose reduction

Akar Y., Yucel G., Durukan A., Yucel M., Arici G.

CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, cilt.33, sa.1, ss.53-59, 2005 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 33 Sayı: 1
Basım Tarihi: 2005
Doi Numarası: 10.1111/j.1442-9071.2005.00942.x
Dergi Adı: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.53-59
Anahtar Kelimeler: administration route, dose reduction, systemic toxicity, tacrolimus, CYCLOSPORINE-A, RENAL-FUNCTION, FK-506, FK506, KIDNEY, TRANSPLANTATION, HYPERLIPIDEMIA, NEPHROTOXICITY, METABOLISM, GLUCOSE
Akdeniz Üniversitesi Adresli: Hayır

Özet

Purpose: To evaluate the long-term systemic toxicity of tacrolimus (FK-506) administered by various routes, and to assess the effect of dose reduction on toxicity.