Must antidysrhythmic agents be given to all patients with new-onset atrial fibrillation?

ERGENE U., ERGENE O., FOWLER J., KINAY O., CETE Y., Oktay C., ...Daha Fazla

AMERICAN JOURNAL OF EMERGENCY MEDICINE, cilt.17, sa.7, ss.659-662, 1999 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 7
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1016/s0735-6757(99)90153-5
  • Dergi Adı: AMERICAN JOURNAL OF EMERGENCY MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.659-662
  • Anahtar Kelimeler: atrial fibrillation, cardioversion, spontaneous conversion, propafenone, ORAL PROPAFENONE, CARDIOVERSION, CONVERSION, THERAPY
  • Akdeniz Üniversitesi Adresli: Evet

Özet

We investigated the spontaneous conversion rate of new-onset atrial fibrillation (AF) in emergency department patients and the recurrence rate of AF during al month follow up period. Sixty-six consecutive hemodynamically stable patients presenting to a university hospital emergency department with new-onset atrial fibrillation (less than 72 hours duration) comprised the study population. Patients were initially monitored for 8 hours and observed for spontaneous conversion of AF to sinus rhythm. If conversion did not occur in the first 8 hours, an oral loading dose (600 mg) of propafenone was given, and patients were observed for an additional 8 hours. All patients were reevaluated at 24 hours and at 1 month, The spontaneous conversion rate in patients presenting within 6 hours of AF onset during the initial 8-hour observation period was 71%. The spontaneous conversion rate for ail patients during the initial observation period was 53%, The conversion rates between patients presenting "early" (less than 6 hours) and "late" (7-72 hours) were significantly different (P < 0.001). Many patients with new-onset AF, especially those with atrial fibrillation duration less than 6 hours, may need observation only, rather than immediate intervention, to treat their dysrhythmia, (Am J Emerg Med 1999;17:659-662. Copyright (C) 1999 by W.B. Saunders Company).