Effects of trimetazidine on submaximal exercise test in patients with acute myocardial infarction

Guler N., Eryonucu B., Gunes A., GÜNTEKİN Ü., Tuncer M., Ozbek H.

CARDIOVASCULAR DRUGS AND THERAPY, cilt.17, sa.4, ss.371-374, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1023/a:1027376529708
  • Dergi Adı: CARDIOVASCULAR DRUGS AND THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.371-374
  • Anahtar Kelimeler: myocardial infarction, trimetazidine, exercise test, CORONARY-ARTERY DISEASE, STABLE ANGINA-PECTORIS, DOUBLE-BLIND, PROPRANOLOL, COMBINATION, DILTIAZEM, EFFICACY, RABBITS, SIZE
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Background: It was demonstrated that the novel metabolic agent, trimetazidine, could lessen the incidence and severity of angina, whether used in monotherapy or combination. Although the animal studies demonstrated that trimetazidine reduces myocardial infarct size and improves recovery of mechanic function after ischemia, little is known on the potential benefits of trimetazidine in patients with acute myocardial infarction (AMI). The aim of this study was to evaluate the efficacy of trimetazidine on AMI by sub-maximal exercise test.