Comparison of initial efficacy and long-term follow-up of heparin-coated Jostent with conventional NIR stent

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Semiz E., Ermis C., Yalcinkaya S., Sancaktar O., Deger N.

JAPANESE HEART JOURNAL, cilt.44, sa.6, ss.889-898, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 6
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1536/jhj.44.889
  • Dergi Adı: JAPANESE HEART JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.889-898
  • Anahtar Kelimeler: coronary stents, coating, heparin, coronary disease, restenosis, PORCINE CORONARY-ARTERIES, PALMAZ-SCHATZ STENTS, BALLOON ANGIOPLASTY, NEOINTIMAL FORMATION, BENESTENT-II, RESTENOSIS, TRIAL, DISEASE, BIOCOMPATIBILITY, IMPLANTATION
  • Akdeniz Üniversitesi Adresli: Evet

Özet

The implantation of heparin-coated stents was reported to be well tolerated. but (here are conflicting, results about acute in-hospital complications, (sub)acute thrombosis rates and long-term fallow-up compared to uncoated stents. We compared the angiographic and clinical results after coronary placement of two stent models: the heparin-coated pre-mounted Jostent and the uncoated premounted NIR stent. Of 7 10 patients revascularized, a total of 426 patients received Jostent (n = 230) or NIR stent (11 = 196) implantation. The primary end points were acute or subacute thrombosis. UF2ent CABG. AMI or death. while the secondary end points were the comparison of the restenosis rates of the stents at the 6(th) month and of the functional angina classification of the Stein groups at the 1(st) 6(th) and 12(th) months. There were no Significant differences between (lie Jostent and NIR stent groups regarding angiographic and procedural success. Acute thrombosis rates in the Jostent and NIR stent groups were similar while no subacute thrombosis was observed in either group. The major adverse cardiac event rates of the groups also did not differ. Angiographic restenosis occurred in 17% of the Jostent group and 16% of (lie NIR stent groups (NS). The combined clinical and angiographic restenosis rate was also Similar between the Jo and NIR groups (19% and 18%. respectively). Comparison of functional angina classes at the 1 6(th) and 12(th) months revealed no significant difference between the study groups.