Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate

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Jacobs P. P., Inan M., Festjens N., Haustraete J., Van Hecke A., Contreras R., ...Daha Fazla

MICROBIAL CELL FACTORIES, cilt.9, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1186/1475-2859-9-93
  • Dergi Adı: MICROBIAL CELL FACTORIES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Yeast expression systems with altered N-glycosylation are now available to produce glycoproteins with homogenous, defined N-glycans. However, data on the behaviour of these strains in high cell density cultivation are scarce.