Platelet activation in subjects with subclinical hypothyroidism

Coban E., Yazıcıoğlu G., Özdoğan M.

MEDICAL SCIENCE MONITOR, cilt.13, sa.4, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 4
  • Basım Tarihi: 2007
  • Dergi Adı: MEDICAL SCIENCE MONITOR
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: cardiovascular risk, platelet activation, mean platelet volume, subclinical hypothyroidism, INDEPENDENT RISK-FACTOR, SMALL-SIZED PLATELETS, MYOCARDIAL-INFARCTION, CARDIOVASCULAR-DISEASE, ROUTINE MEASUREMENT, VASCULAR-DISEASE, HEART-DISEASE, ELDERLY-WOMEN, ATHEROSCLEROSIS, VOLUME
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Coronary heart disease is the major cause of death in the developed world. Platelet activation and aggregation are central processes in the pathophysiology of coronary heart disease. Mean platelet volume (MPV), a determinant of platelet function, is a newly emerging risk factor for atherothrombosis. The present study was designed to evaluate levels of MPV in subclinical hypothyroidic subjects compared with euthyroidic subjects in a cross-sectional study.