The role of selenium in bevacizumab induced cardiotoxicity


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Oncel C. R., Ovey I. S.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.120, no.2, pp.131-138, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 120 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.4149/bll_2019_021
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.131-138
  • Keywords: apoptosis, bevacizumab, cardiomyocyte, transient receptor potential vanilloid 1, selenium, MITOCHONDRIAL OXIDATIVE STRESS, ENDOTHELIAL GROWTH-FACTOR, CANCER CELLS INVOLVEMENT, CARDIAC-HYPERTROPHY, CHANNEL EXPRESSION, CALCIUM OVERLOAD, HEART-FAILURE, TRPV1, APOPTOSIS, RECEPTOR
  • Akdeniz University Affiliated: Yes

Abstract

OBJECTIVE: We investigated the role of selenium in bevacizumab induced cardiotoxicity and involvement of transient receptor potential vanilloid 1 (TRPV1) channels in cardiomyocytes.