Total Antioxidant Capacity, Hydrogen Peroxide, Malondialdehyde and Total Nitric Oxide Concentrations in Patients with Severe Persistent Allergic Asthma: Its Relation To Omalizumab Treatment

Yalcin A. D., Gorczynski R. M., Parlak G. E., Kargi A., Bisgin A., Sahin E., ...Daha Fazla

CLINICAL LABORATORY, cilt.58, sa.1-2, ss.89-96, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 58 Sayı: 1-2
  • Basım Tarihi: 2012
  • Dergi Adı: CLINICAL LABORATORY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.89-96
  • Anahtar Kelimeler: Omalizumab, allergic asthma, antioxidant, hydrogen peroxide, malondialdehyde, nitric oxide, ANTI-IGE ANTIBODY, IMMUNOTHERAPY, RHINITIS, STRESS, ANAPHYLAXIS, ENDOTHELIN, EFFICACY, MODELS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Asthma is a chronic inflammatory disease and omalizumab is indicated for moderate-to-severe persistent asthma. The results of many studies have shown that oxidative stress is involved in asthma pathogenesis. However, there is no data available to evaluate the alterations in total antioxidant capacity, hydrogen peroxide, malondialdehyde, and total nitric oxide concentrations.