Prostaglandins, capsaicin-sensitive sensory nerves and neutrophil infiltration, but not nitric oxide, contribute to cold restraint stress-induced gastric adaptation in rats


Tan R., Bulbul M., Ongut G., Tosun O., Izgut-Uysal V. N.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol.33, no.10, pp.946-951, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 10
  • Publication Date: 2006
  • Doi Number: 10.1111/j.1440-1681.2006.04469.x
  • Journal Name: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.946-951
  • Keywords: calcitonin gene-related peptide, capsaicin, cold restraint stress, gastric adaptation, nitric oxide, prostaglandin E2, MUCOSAL LESIONS, ADAPTIVE CYTOPROTECTION, LIPID-PEROXIDATION, SYNTHASE ACTIVITY, INJURY, ACID, CYCLOOXYGENASE, PROSTACYCLIN, PROTECTION, NEURONS
  • Akdeniz University Affiliated: Yes

Abstract

The aim of the present study was to determine the role of prostaglandins (PG), nitric oxide (NO) and capsaicin-sensitive sensory nerves in neutrophil infiltration in gastric adaptation to cold restraint stress in rats.