Effects of long- and short-term darbepoetin-alpha treatment on oxidative stress, inflammation and endothelial injury in ApoE knockout mice

OZDEMIR, Evrim; Hanikoglu, AYŞEGÜL; Cort, Aysegul; ÖZBEN SADIÇ, BESTE; SÜLEYMANLAR, GÜLTEKİN; Ozben, TOMRİS

doi:10.17219/acem/62834

Effects of long- and short-term darbepoetin-alpha treatment on oxidative stress, inflammation and endothelial injury in ApoE knockout mice

OZDEMIR E. D., Hanikoglu A., Cort A., ÖZBEN SADIÇ B., SÜLEYMANLAR G., Ozben T.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.26, sa.4, ss.635-643, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 26 Sayı: 4
Basım Tarihi: 2017
Doi Numarası: 10.17219/acem/62834
Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.635-643
Anahtar Kelimeler: oxidative stress, atherosclerosis, endothelial dysfunction, darbepoetin-alpha, ApoE knockout mice, E-DEFICIENT MICE, ATHEROSCLEROTIC LESIONS, APOLIPOPROTEIN, HYPERCHOLESTEROLEMIA, INTERLEUKIN-6, EXPRESSION, HISTAMINE, FAILURE, RELEASE
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Akdeniz Üniversitesi Adresli: Evet

Özet

Background. Atherosclerosis and atherosclerosis-related complications are the main cause of death in the world. Vascular injury in response to inflammation and enhanced oxidant stress promotes endothelial dysfunction and leads to atherosclerotic lesions.