Efficacy of regorafenib in the second-and third-line setting for patients with advanced hepatocellular carcinoma: A real life data of multicenter study from Turkey

Hacioglu, Muhammet; Kostek, Osman; Karabulut, Senem; Tastekin, Didem; SEZGİN GÖKSU, SEMA; Alandag, Celal; Akagunduz, Baran; Bilgetekin, Irem; Caner, Burcu; ŞAHİN, AHMET; Yildiz, Birol; Kose, Fatih; Kaplan, Muhammet; Gulmez, Ahmet; Dogan, Ender; Guven, Deniz; Gurbuz, Mustafa; Ergun, Yakup; KARAAĞAÇ, MUSTAFA; Demiray, Atike; Turker, Sema; Sakalar, Teoman; Ozkul, Ozlem; Telli, Tugba; Sahin, Suleyman; KILIÇKAP, SAADETTİN; Bilici, Ahmet; ERDOĞAN, BÜLENT; ÇİÇİN, İRFAN

Efficacy of regorafenib in the second-and third-line setting for patients with advanced hepatocellular carcinoma: A real life data of multicenter study from Turkey

Hacioglu M. B., Kostek O., Karabulut S., Tastekin D., SEZGİN GÖKSU S., Alandag C., ...More

JOURNAL OF BUON, vol.25, no.4, pp.1897-1903, 2020 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 25 Issue: 4
Publication Date: 2020
Journal Name: JOURNAL OF BUON
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
Page Numbers: pp.1897-1903
Keywords: hepatocellular carcinoma, regorafenib, disease control rate, overall survival, chemotherapy, anti-VEGF therapy, SORAFENIB, CANCER
Akdeniz University Affiliated: Yes

Abstract

Purpose: After failure of the first-line sorafenib treatment in advanced or metastatic stage hepatocellular carcinoma (HCC), regorafenib is one of the newly-approved targeted agents. We aimed to evaluate the efficacy of regorafenib in patients with advanced HCC treated in the secondor third-line setting.