Investigation of ACE Genome Insertion/Deletion Correlation with Immunohistochemical Profile in Pituitary Adenomas

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Altas M., Bayrak O. F., SEREFHAN A., Silav G., COSKUN K. K., CERCI A., ...More

TURKISH NEUROSURGERY, vol.23, no.4, pp.464-469, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.5137/1019-5149.jtn.7423-12.0
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.464-469
  • Keywords: Angiotensin-converting enzyme, Pituitary adenomas, Gene, CONVERTING-ENZYME GENE, BREAST-CANCER RISK, ANGIOTENSIN-II, ANTERIOR-PITUITARY, DELETION POLYMORPHISM, EXPRESSION, RELEASE, GROWTH, IMMUNOREACTIVITY, INHIBITORS
  • Akdeniz University Affiliated: Yes

Abstract

AIM: The deletion polymorphism of the angiotensin-converting enzyme (ACE) genome causes neoplastic development in several organs by increasing the angiotensin 2 (A2) formation. In this study, we aimed to identify the ACE genome insertion/deletion polymorphism in pituitary adenomas and to compare it with the control group.