Systemic treatment with alpha-tocopherol and/or sodium selenite decreases the progression of experimental periodontitis

BAS N., KAYAR N. A., BABA Z. F., Avunduk M. C., Haliloglu S., Alptekin N. O.

CLINICAL ORAL INVESTIGATIONS, cilt.25, sa.5, ss.2677-2688, 2021 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 5
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s00784-020-03579-9
  • Dergi Adı: CLINICAL ORAL INVESTIGATIONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.2677-2688
  • Anahtar Kelimeler: Animal model, Experimental periodontitis, alpha-Tocopherol, Sodium selenite, CD95, iNOS, IL-1 beta, IL-6, IL-4, NITRIC-OXIDE SYNTHASE, HUMAN GINGIVAL FIBROBLASTS, INDUCED OXIDATIVE DAMAGE, KAPPA-B ACTIVATION, VITAMIN-E, BETA-CAROTENE, DIABETES-MELLITUS, BONE METABOLISM, INOS EXPRESSION, UP-REGULATION
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective To investigate the effects of sodium selenite (Se) and/or alpha-tocopherol (alpha T) applications on the alveolar bone loss (ABL), the number of gingival collagen fibers, inducible nitric oxide synthase (iNOS)+ and CD95+ cell numbers, and serum cytokine concentrations in experimental periodontitis in rats.