Effect of Gibberellic Acid on the Levels of Tumor Necrosis Factor-alpha, Interleukin-4 and Interleukin-10 in Rats

OZTURK H. B. A., ERİN N., BALCI M. K.

TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM, cilt.23, sa.3, ss.150-157, 2019 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 3
  • Basım Tarihi: 2019
  • Doi Numarası: 10.25179/tjem.2019.69107
  • Dergi Adı: TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.150-157
  • Anahtar Kelimeler: Gibberellic acid, tumor necrosis factor-alpha, interleukin-4, interleukin-10, rat, ISOLATED LIMB PERFUSION, BUFO-REGULARIS, GROWTH, INHIBITION, INDUCTION, NEOPLASMS, PROMOTER, CANCER, IL-10, CELLS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: Gibberellic acid is a plant growth factor. Several studies have demonstrated the effect of gibberellic acid on tumor development. Tumor necrosis factor-alpha, interleukin-4 and interleukin-10 are important cytokines involved in the regulation or prevention of cancer. The aim of this study was to investigate whether changes in cytokine balance have any role in the tumor-inducing effect of gibberellic acid.