The effects of 4-chlorophenoxyacetic acid-raised tomato homogenate on rat erythrocyte antioxidant enzymes

Ozdem S., Ozdem S., Aliciguzel Y.

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, cilt.67, sa.2, ss.134-136, 2000 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Sayı: 2
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1006/pest.2000.2486
  • Dergi Adı: PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.134-136
  • Akdeniz Üniversitesi Adresli: Evet

Özet

We studied the effect of 4-chlorophenoxyacetic acid-raised tomato homogenate on rat erythrocyte antioxidant enzymes, namely glucose-6-phosphate dehydrogenase, catalase, selenium-dependent glutathione peroxidase, and Cu/Zn-superoxide dismutase. Tomatoes were raised with 1, 10, or 20 ppm of 4-chlorophenoxyacetic acid by spraying. Homogenate of tomatoes raised with 1 or 10 ppm of 4-chlorophenoxyacetic acid given in a dose of 1 ml/100 g body weight by gavage did not cause any significant alterations in activities of rat erythrocyte antioxidant enzymes. However, homogenate of tomatoes raised with 20 ppm 4-chlorophenoxyacetic acid given in the same dose caused a significant reduction in selenium-dependent glutathione peroxidase (P < 0.05) and an increment in catalase (P < 0.05) activities but did not significantly alter the activities of other enzymes. It is suggested that the alterations in activities of erythrocyte antioxidant enzymes might play a role in toxic effects of phenoxyherbicides. (C) 2000 Academic Press.