Modified experimental mild traumatic brain injury model

Ucar T., TANRIÖVER G., GÜRER İ. E., Onal M., Kazan S.

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, vol.60, no.3, pp.558-565, 2006 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 60 Issue: 3
  • Publication Date: 2006
  • Doi Number: 10.1097/01.ta.0000209172.75637.db
  • Journal Name: JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.558-565
  • Keywords: mild head injury, experimental, model, LATERAL FLUID-PERCUSSION, CEREBRAL-BLOOD-FLOW, HEAD-INJURY, AXONAL INJURY, RATS, PATHOPHYSIOLOGY, PATTERNS
  • Akdeniz University Affiliated: Yes

Abstract

Background: Experimental models of traumatic brain injury (TBI), using a variety of techniques and species, have been devised with the aim of producing repeatable lesions resembling those found in head injuries. There are various TBI models mentioned in the literature. In experimental head trauma models, emphasis has been placed on the severe head injuries. There are only a few models developed to study mild traumatic brain injury (MTBI). In fact, MTBI is as an important a problem as severe head injuries for neurosurgeons.