Plasma thiol/disulphide homeostasis changes in patients with restless legs syndrome

Kucuksayan E., Ozben S., Tuac S. T., Koseoglu M., EREL Ö., NEŞELİOĞLU S., ...Daha Fazla

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, cilt.59, sa.7, ss.1257-1265, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 59 Sayı: 7
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1515/cclm-2020-1659
  • Dergi Adı: CLINICAL CHEMISTRY AND LABORATORY MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1257-1265
  • Anahtar Kelimeler: disulphide, native thiol, oxidative stress, restless legs syndrome, thiol disulphide homeostasis, total thiol, THIOL-DISULFIDE HOMEOSTASIS, OXIDATIVE STRESS MARKER, REACTIVE OXYGEN, NITRIC-OXIDE, DISEASE, GLUTATHIONE, INHIBITION, IMPAIRMENT, APOPTOSIS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objectives: Restless legs syndrome (RLS) is a common neurological condition. Oxidative stress plays an important role in its pathogenesis. Thiol-disulphide homeostasis (TDH) is a new biomarker of oxidative stress. We studied plasma TDH to determine whether TDH could be used as a new biomarker for RLS and evaluated correlations between TDH and various disease severity rating scales.