Akademik Veri Yönetim Sistemi
2025 IADR/PER General Session & Exhibition (Barcelona, Spain, Barcelona, İspanya, 25 - 28 Haziran 2025, ss.181, (Özet Bildiri)
Objectives: To investigate the relationship between caries incidence and bisphosphonate use in patients, compared to systemically healthy individuals.
Methods: This retrospective cohort study encompassed 100 participants: 50 individuals receiving bisphosphonate therapy and 50 age- and gender-matched healthy controls. All participants presented to the Faculty of Dentistry, Akdeniz University, between 2013 and 2023. Panoramic radiographs were utilized to assess dental health indicators, including caries prevalence, restorations, and the number of intact teeth. Third molars were excluded from the analysis. Two experienced dentists independently evaluated the radiographs, adhering to standardized criteria. Inclusion criteria encompassed patients aged 18 to 70 years, while exclusion criteria included individuals with substantial tooth loss, crowns, implants, or significant radiographic artifacts. The outcome measures were the DMF index, the number of teeth with caries, the number of restored teeth, and the number of intact teeth. Statistical analysis was conducted using the independent samples t-test to compare these parameters between the bisphosphonate and control groups (p < 0.05).
Results: The mean DMF index was 8.42 for healthy individuals and 9.32 for bisphosphonate users, with no statistically significant difference between the groups (p = 0.26). Similarly, there were no significant differences in the number of sound teeth (20.12 vs. 20.32, respectively; p = 0.59), restored teeth (3.0 vs. 2.4, respectively; p = 0.08), or carious teeth (2.08 vs. 2.34, respectively; p = 0.52).
Conclusions: There was no statistically significant difference between bisphosphonate users and healthy individuals in terms of the DMF index, the number of sound teeth, restored teeth, or carious teeth. The slight increase in the DMF index among bisphosphonate users was not significant. Further studies with larger sample sizes are recommended to confirm these findings.