Uterine cervical carcinosarcoma; very rare and aggressive behavior; literature review

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BİRGE Ö., Bakir M. S., KARADAĞ C., DİNÇ C., ŞİMŞEK T.

CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY, cilt.48, sa.2, ss.448-452, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 48 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.31083/j.ceog.2021.02.2219
  • Dergi Adı: CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Sayfa Sayıları: ss.448-452
  • Anahtar Kelimeler: Carcinosarcoma, Uterine cervix, Paramesonephric, Mesonephric, Hypercalcemia, TUMOR, RADIOTHERAPY, SURVIVAL, SARCOMAS, THERAPY, UTERUS, IMPACT
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Carcinosarcoma is a rare malignancy of the female reproductive system, consisting of carcinomatous and sarcomatous components. It originates from the paramesonephric and mesonephric duct residues and is also called malignant mixed Mullerian tumor. Case Presentation: A 58-year-old post-menopausal woman, gravida 2, parity 2, who had no known diseases and no previous surgery presented to another clinic with pelvic pain that had been persisting for about a year and vaginal bleeding for the past month. There was continuous bleeding that was not associated with coitus, and cervical biopsy was reported as carcinosarcoma of heterologous type (the epithelial part was serous carcinoma and the mesenchymal part was chondrosarcoma); the patient was referred to our clinic and underwent evaluation. Conclusion: Effective follow-up is very important considering the aggressive clinical picture of carcinosarcoma cases. It should be kept in mind that metastasis may occur, especially in cases with hypercalcemia and deterioration of the general condition.