Aloe Vera and Cancer

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Unlu A., Nayir E., AY H., Kirca O., Ozdogan M.

TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY, vol.31, no.2, pp.68-72, 2016 (ESCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 31 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.5505/tjo.2016.1433
  • Journal Name: TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.68-72
  • Keywords: Aloe barbadensis, Aloe capensis, Aloe vera, alternative medicine, cancer, phytotherapy, IN-VITRO, CELL-CYCLE, PHASE-III, EMODIN, GEL, CHEMOTHERAPY, INHIBITION, HEPATITIS, ARREST, AGENT
  • Akdeniz University Affiliated: Yes

Abstract

Aloe vera, a succulent plant species, has a long history in folk medicine. Its clear, viscous liquid has been used to treat skin problems and other disorders since ancient times. In the last century, oral consumption and the injection of aloe have also come to popular attention. Its topical use is effective in the treatment of burns and abrasions, and oral use is effective in the treatment of constipation. However, it has not been found to be superior to standard treatments. Most recently, claims of anti-cancer properties are prevalent. It has been found to inhibit proliferation and angiogenesis, and to induce apoptosis in cancer cells. Yet other clinical studies indicate that Aloe vera did not prevent or reduce the number of radiotherapy-related lesions; it merely delayed onset. Furthermore, many instances of toxicity and mortality have been reported in the literature. Today, it is better to avoid it, especially forms taken orally or by injection.