In Vivo Fluorescence Imaging is Well-Suited for the Monitoring of Adenovirus Directed Transgene Expression in Living Organisms

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KAHRAMAN S., DIRICE E., ŞANLIOĞLU A. D., Yoldas B., Bagci H., ERKILIÇ M., ...More

MOLECULAR IMAGING AND BIOLOGY, vol.12, no.3, pp.278-285, 2010 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 12 Issue: 3
• Publication Date: 2010
• Doi Number: 10.1007/s11307-009-0260-x
• Journal Name: MOLECULAR IMAGING AND BIOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.278-285
• Keywords: In vivo imaging, CCD camera, EGFP, Adenoviral vector, Gene therapy, GENE-THERAPY, NECROSIS, VECTORS, PROTEIN, GREEN, CELLS, LUCIFERASE, DELIVERY, TUMORS, SIRNA
• Akdeniz University Affiliated: Yes

Abstract

We tested a new light detection cooled charge-coupled device (CCD) for in vivo assessment of noninvasive, whole-body fluorescence optical imaging of adenovirus directed enhanced green fluorescent protein (AdEGFP) expression.