An investigation on antioxidant and antimicrobial activities of four Inula helenium L. taxa

ALBAYRAK S., Cinar A. E. K., Paksoy M. Y., AKSOY A.

IRANIAN JOURNAL OF SCIENCE AND TECHNOLOGY TRANSACTION A-SCIENCE, vol.39, no.A4, pp.473-483, 2015 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: A4
  • Publication Date: 2015
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.473-483
  • Keywords: Inula helenium, antimicrobial activity, antioxidant activity, DPPH, ESSENTIAL OIL, PHENOLIC CONTENT, FLAVONOIDS
  • Akdeniz University Affiliated: Yes


The antioxidant activities of methanol (ME), ethanol (EE), water (WE) and ethyl acetate (EAE) extracts of four Inula helenium L. taxa (I. helenium ssp. orygalis (Boiss.) Grierson, I. helenium ssp. pseudohelenium Grierson, I. helenium ssp. turcarasemosa Grierson and I. helenium ssp. vanensis Grierson) were investigated. The phosphomolybdenum assay, beta-carotene linoleate bleaching and DPPH radical scavenging activity were used to evaluate the antioxidant capacity. The total phenolic contents determined by Folin-Ciocalteu assay of the extracts ranged from 4.18 to 102.91 mg gallic acid equivalents (GAE)/g dry extract. The extracts showed considerable effect on reducing the oxidation of beta-carotene. The highest radical scavenging activity was obtained for ME of I. helenium ssp. orygalis in DPPH assay. ME, EE and EAE of four Inula helenium taxa showed significant antibacterial activity against 13 bacteria tested. WEs had no inhibitory effect against bacteria tested except for I. helenium ssp. orygalis. EE of I. helenium ssp. orygalis was only effective against C. albicans.