A multicenter experience of thrombotic microangiopathies in Turkey: The Turkish Hematology Research and Education Group (ThREG)-TMA01 study


Tekgunduz E., YILMAZ M., ERKURT M. A., Kiki I., Kaya A. H., Kaynar L., ...More

TRANSFUSION AND APHERESIS SCIENCE, vol.57, no.1, pp.27-30, 2018 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 57 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.1016/j.transci.2018.02.012
  • Journal Name: TRANSFUSION AND APHERESIS SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.27-30
  • Keywords: Thrombotic microangiopathy, Thrombotic thrombocytopenic purpura, Hemolytic-uremic syndrome, TTP, HUS, HEMOLYTIC-UREMIC SYNDROME, THROMBOCYTOPENIC PURPURA, ADULT PATIENTS, DIAGNOSIS, MANAGEMENT, REGISTRY, AHUS, TTP, ECULIZUMAB, CONSENSUS
  • Akdeniz University Affiliated: Yes

Abstract

Thrombotic microangiopathies (TMAs) are rare, but life-threatening disorders characterized by microangiopathic hemolytic anemia and thrombocytopenia (MAHAT) associated with multiorgan dysfunction as a result of microvascular thrombosis and tissue ischemia. The differentiation of the etiology is of utmost importance as the pathophysiological basis will dictate the choice of appropriate treatment.