Is the cell death in mesial temporal sclerosis apoptotic?

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Uysal H., CEVIK I., SOYLEMEZOGLU F., ELIBOL B., Gursoy-Ozdemir Y., EVRENKAYA T., ...Daha Fazla

EPILEPSIA, cilt.44, sa.6, ss.778-784, 2003 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 6
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1046/j.1528-1157.2003.37402.x
  • Dergi Adı: EPILEPSIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.778-784
  • Anahtar Kelimeler: epilepsy, cell death, Bcl-2, Bax, caspases, BAX PROTEIN EXPRESSION, ALZHEIMERS-DISEASE, DNA FRAGMENTATION, CEREBRAL-ISCHEMIA, NEURONAL DEATH, BCL-X, BRAIN, DAMAGE, IMMUNOREACTIVITY, HIPPOCAMPUS
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose: Mesial temporal sclerosis (NITS) is characterized by neuronal loss in the hippocampus. Studies on experimental models and patients with intractable epilepsy suggest that apoptosis may be involved in neuronal death induced by recurrent seizures.