Role of a hyaluronic-acid derivative in preventing surgical adhesions and abscesses related to dropped bile and gallstones in an experimental model

Aytekin F. O., Tekin K., Kabay B., Erdem E., Erbis H., Ozden A.

AMERICAN JOURNAL OF SURGERY, cilt.188, sa.3, ss.288-293, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 188 Sayı: 3
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/j.amjsurg.2004.06.006
  • Dergi Adı: AMERICAN JOURNAL OF SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.288-293
  • Anahtar Kelimeler: adhesion, cholecystectomy, hyaluronic acid, laparoscopy, adverse effects, RAT PERITONITIS MODEL, LAPAROSCOPIC CHOLECYSTECTOMY, SPILLED GALLSTONES, LOST GALLSTONES, POSTSURGICAL ADHESIONS, ABDOMINAL ADHESIONS, REDUCTION, COMPLICATIONS, MEMBRANE, SURGERY
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Background: Despite its advantages, iatrogenic gallbladder perforation with resultant spillage of bile and gallstones is not uncommon during laparoscopic cholecystectomy. Although this is not generally considered a significant problem, spilled gallstones may cause problems even years after the operation. Hyaluronic acid has been introduced into clinical practice and successfully used to decrease postoperative adhesions after abdominopelvic surgery. In this study, we investigated the effectiveness of a hyaluronic-acid derivative in preventing complications related to spilled gallstones and bile leakage in an experimental study.