LC-MS/MS analysis of plasma polyunsaturated fatty acids in type 2 diabetic patients after insulin analog initiation therapy

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Aslan M., Ozcan F., Aslan I., Yucel G.

LIPIDS IN HEALTH AND DISEASE, cilt.12, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1186/1476-511x-12-169
  • Dergi Adı: LIPIDS IN HEALTH AND DISEASE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Polyunsaturated fatty acids, Diabetes mellitus, Insulin, Prostaglandin, ALPHA-LINOLENIC ACID, EICOSAPENTAENOIC ACID, GENE-EXPRESSION, DESATURATION, INFLAMMATION, LIPIDS, OMEGA-3-FATTY-ACIDS, PHOSPHOLIPIDS, KETOACIDOSIS, MODULATION
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Eicosanoids derived from omega-6 (n6) polyunsaturated fatty acids (PUFAs) have proinflammatory functions whereas eicosanoids derived from omega-3 (n3) PUFAs have anti-inflammatory properties. This study was designed to evaluate the effect of insulin analog initiation therapy on n6 and n3 PUFAs in type 2 diabetic patients during early phase.