Behcet's Disease: Current Aspects in the Etiopathogenesis

Akman A., ALPSOY E.

TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, cilt.43, ss.32-38, 2009 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43
  • Basım Tarihi: 2009
  • Dergi Adı: TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.32-38
  • Anahtar Kelimeler: Behcet's disease, aetiopathogenesis, genetic factors, infectious agents, immunologic system, TURKISH PATIENTS, PERIODONTAL FINDINGS, GENE POLYMORPHISMS, T-CELLS, STRONG ASSOCIATION, CLOSE ASSOCIATION, ENDOTHELIAL-CELLS, JAPANESE PATIENTS, INTERFERON-GAMMA, MIC-A
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Behcet's disease (BD) is a chronic, relapsing, systemic vasculitis. The aetiology of BID remains unknown, but the most widely held hypothesis of the disease pathogenesis is that an altered immune response triggered by an infectious agent or by an otoantigen in a genetically susceptible host. In this paper, we aimed to overview the main aetiopathogenetic hypotheses for the disease including genetic factors, infectious agents and immunologic abnormalities. (Turkderm 2009; 43 Suppl 2: 32-8)