Importance of TNF-related apoptosis-inducing ligand in pathogenesis of interstitial cystitis

Kutlu Ö., Akkaya E., KÖKSAL İ. T., Bassorgun I. C., Ciftcioglu M. A., ŞANLIOĞLU S., ...More

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.42, no.2, pp.393-399, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 2
  • Publication Date: 2010
  • Doi Number: 10.1007/s11255-009-9632-z
  • Journal Name: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.393-399
  • Keywords: Interstitial cystitis, TRAIL, Apoptosis, Pathogenesis, TRAIL-INDUCED APOPTOSIS, NF-KAPPA-B, URINARY-BLADDER, INTRAVESICAL POTASSIUM, PROSTATE CARCINOMA, CELLS, EXPRESSION, RECEPTORS, MICE, GLYCOSAMINOGLYCANS
  • Akdeniz University Affiliated: Yes

Abstract

Although interstitial cystitis is an inflammatory disease, its etiopathogenesis is not clearly understood. The objective of the present study is to investigate the distribution of TNF-related apoptosis-inducing ligand (TRAIL) and its receptors in bladder biopsy samples of patients diagnosed with interstitial cystitis and the role of TRAIL in the pathogenesis of interstitial cystitis.