Human TLR gene family members are differentially expressed in patients with urothelial carcinoma of the bladder

Sabah-Ozcan S., Baser A., Olcucu T., BARIŞ İ. C., Elmas L., Tuncay L., ...More

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, vol.35, no.12, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 12
  • Publication Date: 2017
  • Doi Number: 10.1016/j.urolonc.2017.07.029
  • Journal Name: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Proinflammatory cytokines, TLR expression, Urine, Urothelial carcinoma, TOLL-LIKE RECEPTORS, CANCER-CELLS, TUMOR MICROENVIRONMENT, PROGRESSION, PATHWAYS, TISSUE, MECHANISMS, PROGNOSIS, PATTERNS, BACTERIA
  • Akdeniz University Affiliated: Yes

Abstract

Purpose: Toll-like receptors (TLRs) have an important role in the activation of both innate and adaptive immunity in response to pathogens and endogenous danger signals from damaged or dying cells. The aim of this study was to determine the relationship between urothelial carcinoma (UC) and TLR expression.