Plasma levels of von Willebrand factor in subjects with isolated impaired fasting glucose

ÇOBAN E., Bostan F.

MEDICAL SCIENCE MONITOR, vol.15, no.4, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 4
  • Publication Date: 2009
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: cardiovascular risk, endothelial dysfunction, impaired fasting glucose, von Willebrand factor, ISCHEMIC-HEART-DISEASE, ENDOTHELIAL DYSFUNCTION, RISK-FACTOR, CARDIOVASCULAR-DISEASE, FOLLOW-UP, TOLERANCE, MORTALITY, MARKER
  • Akdeniz University Affiliated: Yes


Background: It has been shown that an increased on Willeband factor level reflects endothelial dysfunction and may also have prognostic value in patients with atherosclerotic disease. Impaired fasting glucose is likely a frequent glycemic disorder in the general population and is considered a prediabetic state. Impaired fasting glucose is associated with cardiovascular disease, but it is unclear whether it is an independent risk factor because it commonly coexists with other cardiovascular risk factors present in metabolic syndrome. The present study was designed to evaluate the von Willebrand factor level in subjects with isolated impaired fasting glucose compared to healthy normoglycemic subjects.