The effect of KNK437, a heat shock protein inhibitor, on angiogenesis of endothelial cells

Sahin E., ŞAHİN M., GÜMÜŞLÜ S.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.42, sa.4, ss.597-604, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.3906/sag-1105-14
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.597-604
  • Anahtar Kelimeler: Hyperthermia, angiogenesis, KNK437, quercetin, tube formation, endothelial cells, IN-VITRO, CANCER, QUERCETIN, THERMOTOLERANCE, HYPERTHERMIA, ACQUISITION, FLAVONOIDS, DISEASES, VIVO
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Aim: Hyperthermia is an effective therapy for cancer and tumor angiogenesis. However, the development of thermotolerance is an important problem. We aimed to investigate the effects of KNK437 and quercetin on angiogenesis and thermotolerance in endothelial cells (ECs).