Prognostic role of Aurora-A expression in metastatic colorectal cancer patients

Goktas S., Yildirim M., Suren D., Alikanoglu A. S., Dilli U. D., Bulbuller N., ...Daha Fazla

JOURNAL OF BUON, cilt.19, sa.3, ss.686-691, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 3
  • Basım Tarihi: 2014
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.686-691
  • Anahtar Kelimeler: Aurora-A, colorectal cancer, metastasis, prognosis, KINASE, CARCINOMA, OVEREXPRESSION, INSTABILITY, SURVIVAL, BREAST, CELLS, GENE
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose: Aurora kinase family plays an important role in mitosis and cell cycle organization. Aurora-A is an important member of the aurora kinase family and its expression increases the genomic instability and contributes to carcinogenesis. In this study, the prognostic role of Aurora-A expression in colorectal cancer (CRC) was assessed.