Prognostic role of Aurora-A expression in metastatic colorectal cancer patients

Goktas S., Yildirim M., Suren D., Alikanoglu A. S., Dilli U. D., Bulbuller N., ...More

JOURNAL OF BUON, vol.19, no.3, pp.686-691, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 3
  • Publication Date: 2014
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.686-691
  • Keywords: Aurora-A, colorectal cancer, metastasis, prognosis, KINASE, CARCINOMA, OVEREXPRESSION, INSTABILITY, SURVIVAL, BREAST, CELLS, GENE
  • Akdeniz University Affiliated: Yes

Abstract

Purpose: Aurora kinase family plays an important role in mitosis and cell cycle organization. Aurora-A is an important member of the aurora kinase family and its expression increases the genomic instability and contributes to carcinogenesis. In this study, the prognostic role of Aurora-A expression in colorectal cancer (CRC) was assessed.