Quantitative comparison of immunohistochemical and PCR analysis of midkine expression in breast cancer types and serum midkine level

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ÇETİN SORKUN H., Akbulut M., ENLİ Y., TEPELİ E., ÖZKAN S., ERDEM E.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.46, no.1, pp.219-227, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.3906/sag-1411-158
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.219-227
  • Keywords: Midkine, breast cancer, serum, immunohistochemistry, real-time quantitative PCR, ELISA, EMBRYONAL CARCINOMA-CELLS, IN-SITU HYBRIDIZATION, PLEIOTROPHIN EXPRESSION, MOUSE EMBRYOGENESIS, MIDGESTATION PERIOD, PROGNOSTIC MARKER, GENE-EXPRESSION, TUMOR, DIFFERENTIATION, SURVIVAL
  • Akdeniz University Affiliated: Yes

Abstract

Background/aim: Midkine (MK), a heparin-binding growth factor, has an important role in cancer progression. The aim of this study was to determine MK expression in breast tissue and the preoperative and postoperative serum levels of patients with breast cancer.