Estradiol suppresses vascular monocyte chemotactic protein-1 expression during early atherogenesis

Seli E., Kayisli U., Selam B., Seli M., Arici A.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, vol.187, no.6, pp.1544-1549, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 187 Issue: 6
  • Publication Date: 2002
  • Doi Number: 10.1067/mob.2002.127306
  • Journal Name: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1544-1549
  • Keywords: estrogen, atherosclerosis, monocyte chemotactic protein-1, mice, aorta, vascular, CHEMOATTRACTANT PROTEIN-1, RECEPTOR-DEFICIENT, INJURY RESPONSE, ATHEROSCLEROSIS, ESTROGEN, MACROPHAGE, MICE, INHIBITION, CELLS
  • Akdeniz University Affiliated: No

Abstract

OBJECTIVE: This study was undertaken to determine whether estrogen down-regulates vascular monocyte chemotactic protein-1 expression during the development of atherosclerosis in vivo and to identify the cellular localization of monocyte chemotactic protein-1 expression under baseline conditions and in response to atherogenic stimuli.