Experimental investigation of relationship between trauma and bisphosphonate-related osteonecrosis

Agacayak K. S., Yuksel H., Atilgan S., Koparal M., Ucan M. C., ÖZGÖZ M., ...More

NIGERIAN JOURNAL OF CLINICAL PRACTICE, vol.17, no.5, pp.559-564, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.4103/1119-3077.141417
  • Journal Name: NIGERIAN JOURNAL OF CLINICAL PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.559-564
  • Keywords: Bisphosphonates, bone, osteonecrosis, prevention, serum C-terminal telopeptide level, RISK-FACTORS, BONE, JAW, PREVENTION, MARKERS, OSTEOCLASTS, EXTRACTION, MANAGEMENT, TURNOVER, CANCER
  • Akdeniz University Affiliated: Yes

Abstract

Background: Bisphosphonate (BP)-related osteonecrosis of the jaw (BRONJ) disease is rare, but there are serious side-effects of BP therapy in patients. In some patients, surgery is needed and could not be cured. A standard test is not available showing the risk of jaw osteonecrosis in routine use. The measurement of serum C-terminal telopeptide (CTX) levels has been used in diseases of BRONJ resorption and antiresorptive therapy.