Experimental investigation of relationship between trauma and bisphosphonate-related osteonecrosis

Agacayak K. S., Yuksel H., Atilgan S., Koparal M., Ucan M. C., ÖZGÖZ M., ...Daha Fazla

NIGERIAN JOURNAL OF CLINICAL PRACTICE, cilt.17, sa.5, ss.559-564, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 5
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4103/1119-3077.141417
  • Dergi Adı: NIGERIAN JOURNAL OF CLINICAL PRACTICE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.559-564
  • Anahtar Kelimeler: Bisphosphonates, bone, osteonecrosis, prevention, serum C-terminal telopeptide level, RISK-FACTORS, BONE, JAW, PREVENTION, MARKERS, OSTEOCLASTS, EXTRACTION, MANAGEMENT, TURNOVER, CANCER
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Bisphosphonate (BP)-related osteonecrosis of the jaw (BRONJ) disease is rare, but there are serious side-effects of BP therapy in patients. In some patients, surgery is needed and could not be cured. A standard test is not available showing the risk of jaw osteonecrosis in routine use. The measurement of serum C-terminal telopeptide (CTX) levels has been used in diseases of BRONJ resorption and antiresorptive therapy.