Low serum copeptin levels in patients with obstructive sleep apnea

Ozben S., Guvenc T. S., Huseyinoglu N., Sanivar H. S., Hanikoglu F., Cort A., ...More

SLEEP AND BREATHING, vol.17, no.4, pp.1187-1192, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.1007/s11325-013-0822-7
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1187-1192
  • Keywords: Obstructive sleep apnea, Copeptin, Antidiuretic hormone, Cardiovascular diseases, ATRIAL-NATRIURETIC-PEPTIDE, POSITIVE AIRWAY PRESSURE, RISK, VASOPRESSIN, HEMORRHAGE, POLYURIA, TROPONIN, NOCTURIA, ADULTS, MEN
  • Akdeniz University Affiliated: Yes


Copeptin, the C-terminal fragment of antidiuretic hormone (ADH), is a new biomarker that has been found to be elevated in several cardiovascular disorders and is related with prognosis. Patients with obstructive sleep apnea demonstrate a tendency to develop coronary and cerebral atherosclerotic disease. Our aim was to investigate copeptin levels in untreated new diagnosed obstructive sleep apnea patients without manifest cardiovascular disorders in order to determine whether copeptin could be used as a biomarker in this group.