Analysis of risk factors predicting (Affecting) mortality and morbidity of peptic ulcer perforations


Arici C., Mesci A., Dincer D., Dinckan A., Colak T.

INTERNATIONAL SURGERY, vol.92, no.3, pp.147-154, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 92 Issue: 3
  • Publication Date: 2007
  • Journal Name: INTERNATIONAL SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.147-154
  • Keywords: peptic ulcer, perforation, risk factors, HELICOBACTER-PYLORI INFECTION, DUODENAL-ULCER, GASTRODUODENAL ULCER, SURGICAL-TREATMENT, EMERGENCY-SURGERY, SIMPLE CLOSURE, DISEASE, ERA, AGE
  • Akdeniz University Affiliated: No

Abstract

The goal of this study is to identify invariable risk factors predicting the morbidity and mortality of a serious complication of peptic ulcer perforation (PUP). One hundred fifty-four patients were operated for PUP. We selected 147 patients who underwent primary repair and omentoplasty for PUP. The Boey score used to determine the high mortality risk after open surgery for PUP. The mortality rates were 0%, 12%, 32%, and 63% in the patients who had zero, one, two, and three factors, respectively (P < 0.001). Total postoperative mortality was 13.6% (20/147). Complications occurred in 48 (32.7%) of a total of 147 patients. Age, pulse rate at admission, and creatinine levels can be independent factors associated with prognosis in PUP.

The goal of this study is to identify invariable risk factors predicting the morbidity and mortality of a serious complication of peptic ulcer perforation (PUP). One hundred fifty-four patients were operated for PUP. We selected 147 patients who underwent primary repair and omentoplasty for PUP. The Boey score used to determine the high mortality risk after open surgery for PUP. The mortality rates were 0%, 12%,32%, and 63% in the patients who had zero, one, two, and three factors, respectively (P < 0.001). Total postoperative mortality was 13.6% (20/147). Complications occurred in 48 (32.7%) of a total of 147 patients. Age, pulse rate at admission, and creatinine levels can be independent factors associated with prognosis in PUP.