Efficacy of 5-Fluorouracil in inhibition of unintended bone formation in spinal surgery: a histological evaluation on a rat model of spontaneous spinal fusion

Kiter E., Er E., Sen Turk N., Oto M., Akkaya S.

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, cilt.48, sa.1, ss.86-91, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3944/aott.2014.3161
  • Dergi Adı: ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.86-91
  • Anahtar Kelimeler: 5-Fluorouracil, inhibition of spinal fusion, spontaneous spinal fusion, FLEXOR TENDON REPAIR, YOUNG-CHILDREN, HARRINGTON INSTRUMENTATION, FIBRIN GLUE, ARTHRODESIS, SCOLIOSIS, TRABECULECTOMY, DEFORMITIES, MANAGEMENT, PROTEIN
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: The aim of this study was to investigate the influence of the antiproliferative agent 5-Fluorouracil (5FU) over inhibition of spinal bone formation in an experimental rat model.