Laparoscopy Can Aggravate the Severity of Pancreatitis in an Experimental Rat Model
JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES, vol.22, no.10, pp.978-983, 2012 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 22 Issue: 10
- Publication Date: 2012
- Doi Number: 10.1089/lap.2012.0328
- Journal Name: JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.978-983
- Akdeniz University Affiliated: Yes
Abstract
Purpose: Over the past decade, laparoscopic techniques have markedly evolved, and it has been shown that minimally invasive surgery can provide a safe, effective, and less traumatic management of various surgical diseases. Additionally, it is well known that pancreatitis itself also produced severe oxidative tissue injury by increasing levels of reactive oxygen species. This study therefore aimed to investigate the effects of pneumoperitoneum on the severity of pancreatitis in a rat model of acute pancreatitis induced by cerulein.