Laparoscopy Can Aggravate the Severity of Pancreatitis in an Experimental Rat Model

Polat, Coskun; Uyar, Hilmi; Bassorgun, CUMHUR; Kahraman, Ahmet; Ciftcioglu, Akif; Arikan, Yuksel

doi:10.1089/lap.2012.0328

Laparoscopy Can Aggravate the Severity of Pancreatitis in an Experimental Rat Model

Polat C., Uyar H., Bassorgun I., Kahraman A., Ciftcioglu A., Arikan Y.

JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES, cilt.22, sa.10, ss.978-983, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 22 Sayı: 10
Basım Tarihi: 2012
Doi Numarası: 10.1089/lap.2012.0328
Dergi Adı: JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.978-983
Akdeniz Üniversitesi Adresli: Evet

Özet

Purpose: Over the past decade, laparoscopic techniques have markedly evolved, and it has been shown that minimally invasive surgery can provide a safe, effective, and less traumatic management of various surgical diseases. Additionally, it is well known that pancreatitis itself also produced severe oxidative tissue injury by increasing levels of reactive oxygen species. This study therefore aimed to investigate the effects of pneumoperitoneum on the severity of pancreatitis in a rat model of acute pancreatitis induced by cerulein.