International Joint Science Congress of Materials and Polymers (ISCMP), Burdur, Turkey, 29 September - 01 November 2021, pp.122, (Summary Text)
In
this study, fibers were obtained by electrospinning technique to increase the
bioavailability of biocompatible polymethyl methacrylate (PMMA)/polyethylene
oxide (PEO)/bis-chalcone derivatives ((2E,6E)‐2,6‐bis(4-nitrobenzylidene)cyclohexanone
and (2E,6E)‐2,6‐bis[(thiophen‐2‐yl)methylene]cyclohexanone) containing
Streptomycin sulfate as a model drug in two different ratios (30 and 60 mg).
The antibacterial effects of drug-containing and non-drug fibers against Bacillus cereus and Escherichia coli were investigated. As a result, it was observed
that the drug-free fibers did not have any antibacterial effect, while the drug-containing
fibers completely destroyed B. cereus
and E. coli. Our findings can provide
insight into new fibers prepared with antimicrobial compounds for wound
dressing applications.