PDCD10, the gene mutated in cerebral cavernous malformation 3, is expressed in the neurovascular unit

Tanriover G., Boylan A. J., DiLuna M. L., Pricola K. L., Louvi A., Gunel M.

NEUROSURGERY, cilt.62, sa.4, ss.930-938, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1227/01.neu.0000318179.02912.ca
  • Dergi Adı: NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.930-938
  • Anahtar Kelimeler: CCM3, expression, gene, neurovascular unit, PDCD10, programmed cell death, CEREBRAL CAVERNOUS MALFORMATION, NEURONAL MIGRATION, MUTATIONS, PROTEIN, KRIT1, CCM1, PATHOGENESIS, BINDING, CELLS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Mutations in the programmed cell death 10 gene, PDCD10, cause the autosomal-dominant familial cerebral cavernous malformation 3 (CCM3). Little is known about the function of this gene in disease pathogenesis.