PDCD10, the gene mutated in cerebral cavernous malformation 3, is expressed in the neurovascular unit

Tanriover, GAMZE; Boylan, Arianne; DiLuna, Michael; Pricola, Katie; Louvi, Angeliki; Gunel, Murat

doi:10.1227/01.neu.0000318179.02912.ca

PDCD10, the gene mutated in cerebral cavernous malformation 3, is expressed in the neurovascular unit

Tanriover G., Boylan A. J., DiLuna M. L., Pricola K. L., Louvi A., Gunel M.

NEUROSURGERY, cilt.62, sa.4, ss.930-938, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 62 Sayı: 4
Basım Tarihi: 2008
Doi Numarası: 10.1227/01.neu.0000318179.02912.ca
Dergi Adı: NEUROSURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.930-938
Anahtar Kelimeler: CCM3, expression, gene, neurovascular unit, PDCD10, programmed cell death, CEREBRAL CAVERNOUS MALFORMATION, NEURONAL MIGRATION, MUTATIONS, PROTEIN, KRIT1, CCM1, PATHOGENESIS, BINDING, CELLS
Akdeniz Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Mutations in the programmed cell death 10 gene, PDCD10, cause the autosomal-dominant familial cerebral cavernous malformation 3 (CCM3). Little is known about the function of this gene in disease pathogenesis.