PDCD10, the gene mutated in cerebral cavernous malformation 3, is expressed in the neurovascular unit

Tanriover G., Boylan A. J., DiLuna M. L., Pricola K. L., Louvi A., Gunel M.

NEUROSURGERY, vol.62, no.4, pp.930-938, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 62 Issue: 4
  • Publication Date: 2008
  • Doi Number: 10.1227/01.neu.0000318179.02912.ca
  • Journal Name: NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.930-938
  • Keywords: CCM3, expression, gene, neurovascular unit, PDCD10, programmed cell death, CEREBRAL CAVERNOUS MALFORMATION, NEURONAL MIGRATION, MUTATIONS, PROTEIN, KRIT1, CCM1, PATHOGENESIS, BINDING, CELLS
  • Akdeniz University Affiliated: Yes

Abstract

OBJECTIVE: Mutations in the programmed cell death 10 gene, PDCD10, cause the autosomal-dominant familial cerebral cavernous malformation 3 (CCM3). Little is known about the function of this gene in disease pathogenesis.