Epilepsia partialis continua in a patient with Behcet's disease

Aktekin B., Dogan E. A., Oguz Y., Karaali K.

CLINICAL NEUROLOGY AND NEUROSURGERY, vol.108, no.4, pp.392-395, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 108 Issue: 4
  • Publication Date: 2006
  • Doi Number: 10.1016/j.clineuro.2004.12.021
  • Journal Name: CLINICAL NEUROLOGY AND NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.392-395
  • Keywords: epilepsia partialis continua, seizure, neurological involvement, Behcet's disease, NEUROLOGICAL INVOLVEMENT, SEIZURES, LESIONS, MOUTH, EYES
  • Akdeniz University Affiliated: No

Abstract

Behqet's disease (BD) is a multisystemic, recurrent, inflammatory disorder of unknown aetiology. Neurological involvement is characterised either by primary parenchymal lesions or secondary to major vascular involvement. Seizures are rarely seen in BD and their occurrence can be related to seizure provoking factors or exacerbation of the disease. We experienced a case of neuro-BD presenting with subacutely developing mental and behavioral changes, followed by left dominant tetraparesis with bilateral pyramidal signs, fever and left hand focal motor seizures with elementery clonic motor signs which later evolved into right hand epilepsia partialis continua (EPC) of Kojevnikov. The seizures were very resistant to antiepileptic drugs and 8 months after neurological involvement the patient died. The EPC evolving after neurological involvement is associated with high mortality rate. (c) 2005 Elsevier B.V. All rights reserved.